7-溴-4-羟基-2H-色烯-2-酮合成路线 （共 4 条）
反应条件
1: m-BrC6H4OAc With sodium hydride in benzene 2: carbonic acid diethyl ester in benzene
参考文献
Grimm, Erich L.; Ducharme, Yves; Frenette, Richard; Friesen, Richard; Gagnon, Marc; Juteau, Helene; Laliberte, Sebastien; MacKay, Bruce; Gareau, Yves
Patent: US2008/188521 A1, 2008 ;
Location in patent: Page/Page column 12 ;
反应条件
in toluene 24 h; Heating / reflux;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/10995 A1, 2004 ;
Location in patent: Page/Page column 40-41 ;
WO 2004/010995 A1
反应条件
sodium in Dowtherm A T=160°C; 2 h;
参考文献
Payne, Sara L.; Rodriguez-Aristegui, Sonsoles; Bardos, Julia; Cano, Celine; Golding, Bernard T.; Hardcastle, Ian R.; Peacock, Marcus; Parveen, Nahida; Griffin, Roger J.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 12 p. 3649 - 3653
参考文献
MERCK FROSST CANADA LTD.
Patent: WO2006/99735 A1, 2006 ;
Location in patent: Page/Page column 29 ;
