1-(2,4-二羟基苯基)-2-(2,4-二甲氧基苯基)乙酮合成路线 （共 9 条）
反应条件
boron trifluoride diethyl etherate T=90 - 100°C; Friedel-Crafts Acylation; 2 h;
参考文献
Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
反应条件
hydrogenchloride; diethyl ether; zinc(II) chloride Erwaermen des Reaktionsprodukts mit Wasser;
参考文献
Bhandari, Prabha; Crombie, Leslie; Daniels, Peter; Holden, Ian; Bruggen, Nicholas Van; Whiting, Donald A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 839 - 850
反应条件
1: 94 percent / K2CO3, Ac2O / dimethylformamide / 6 h 3: 1.) ZnCl2, HCl, 2.) H2O / 1.) Et2O, 0-5 deg C View Scheme
参考文献
Bhandari, Prabha; Crombie, Leslie; Daniels, Peter; Holden, Ian; Bruggen, Nicholas Van; Whiting, Donald A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 839 - 850
反应条件
2: 1.) ZnCl2, HCl, 2.) H2O / 1.) Et2O, 0-5 deg C View Scheme
参考文献
Bhandari, Prabha; Crombie, Leslie; Daniels, Peter; Holden, Ian; Bruggen, Nicholas Van; Whiting, Donald A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 839 - 850
反应条件
1: 65 percent / piperidine / dimethylformamide / 2 h / Heating 2: 73 percent / AlCl3 / acetonitrile / 3 h / Heating View Scheme
参考文献
Bhandari, Prabha; Crombie, Leslie; Daniels, Peter; Holden, Ian; Bruggen, Nicholas Van; Whiting, Donald A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 839 - 850
反应条件
1: acetone; potassium carbonate / Behandeln des Reaktionsprodukts mit methanol. Kalilauge 2: aniline hydrochloride View Scheme
参考文献
Emerson; Bickoff
Journal of the American Chemical Society, 1958 , vol. 80, p. 4381
反应条件
1: sodium acetate
2: aq.-ethanolic hydrochloric acid
3: potassium carbonate; acetone
View Scheme
参考文献
Sehgal; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1955 , # 42 p. 36,38, 39
反应条件
1: diethyl ether
2: sodium
View Scheme
参考文献
Spaeth; Schlaeger
Chemische Berichte, 1940 , vol. 73, p. 1,7
反应条件
1: K2CO3 / acetone
2: 0.65 g / diethylamine / methanol / 2 h / Heating
3: 0.30 g / AlCl3 / acetonitrile / 8 h / Heating
View Scheme
参考文献
Nabaei-Bidhendi; Bannerjee
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 4 p. 366 - 368
