1,2-O-异亚丙基-D-呋喃葡萄糖合成路线 （共 73 条）
反应条件
1: NaIO4 / methanol; H2O / 0.5 h / Ambient temperature
2: NaBH4 / H2O; methanol / 0.5 h / Ambient temperature
3: NaH / dimethylformamide / 13.5 h / Ambient temperature
4: 75 percent / trimethylsilyl trifluoromethanesulfonate (TMSOTf), Et3SiH / CH2Cl2 / 18.5 h / Ambient temperature
5: 97 percent / DMAP, Et3N / CH2Cl2 / 2 h / Ambient temperature
6: 49.5 percent / K2CO3, 18-crown-6 / dimethylformamide / 20 h / 120 °C
7: 78 percent / BCl3 / hexane; CH2Cl2 / 1.) -78 deg C, 2.5 h; 2.) -18 deg C, 4 h
View Scheme
参考文献
Kakefuda, Akio; Shuto, Satoshi; Nagahata, Takemitsu; Seki, Jun-Ichi; Sasaki, Takuma; Matsuda, Akira
Tetrahedron, 1994 , vol. 50, # 34 p. 10167 - 10182
反应条件
pyridine
Ambient temperature;
参考文献
Grishkovets, V. I.; Zemlyakov, A. E.; Chirva, V. Ya.
Chemistry of Natural Compounds, 1982 , vol. 18, # 4 p. 388 - 392
Khimiya Prirodnykh Soedinenii, 1982 , # 4 p. 422 - 426
反应条件
1: 1.) Bu2SnO / 1.) MeOH, reflux, 3 h, 2.) dioxane, from 5 deg C to 10 deg C, 1 h
2: 89 percent / pyridine
3: 6.1 percent / (Bu3Sn)2 / benzene / 4 h / 10 - 15 °C / Irradiation
View Scheme
参考文献
Tsuda, Yoshisuke; Sato, Yoshiyuki; Kanemitsu, Kimihiro; Hosoi, Shinzo; Shibayama, Kenji; Nakao, Kayo; Ishikawa, Yuko
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 8 p. 1465 - 1475
