5a-雄甾烷-3a,17b-二醇合成路线 （共 45 条）
反应条件
Mn(2,2,6,6-tetramethylheptane-3,5-dionate)3; phenyl silane; oxygen in 1,2-dichloro-ethane; isopropyl alcohol T=23°C; P=760 Torr;
参考文献
Magnus, Philip; Fielding, Mark R
Tetrahedron Letters, 2001 , vol. 42, # 38 p. 6633 - 6636
反应条件
potassium tri-sec-butyl-borohydride in tetrahydrofuran T=-80 - 20°C; Inert atmosphere;
参考文献
Steroids, , vol. 76, # 5 p. 478 - 483
反应条件
sulfuric acid; acetic acid Hydrogenation.weiteres Reagens: Platin; Kochen des Reaktionsprodukts mit aethanol. Alkalilauge;
参考文献
FR797903 , ;
US2209004 , ;
CH184420 , ;
Helvetica Chimica Acta, , vol. 18, p. 210,215
反应条件
sodium tetrahydroborate; cerium(III) chloride in methanol Yield given. Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 103, # 18 p. 5454 - 5459
反应条件
anhydrous potassium sulfate; dipotassium peroxodisulfate; acetic acid T=25°C; weiteres Reagens: konz. Schwefelsaeure; Behandeln des Reaktionsprodukts mit aethanol. KOH;
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2621,2624
反应条件
potassium carbonate in methanol T=20°C; 24 h;
参考文献
Hanson, James R.; Hunter, A. Christy
Journal of Chemical Research - Part S, 2003 , # 4 p. 216 - 217
反应条件
Aspergillus tamarii KITA in N,N-dimethyl-formamide 24 h;
参考文献
Journal of Steroid Biochemistry and Molecular Biology, , vol. 118, # 3 p. 171 - 176
反应条件
1: 2.83 g / triphenylphosphine; diethyl azodicarboxylate / toluene / 20 °C 2: 1.8 g / aq. K2CO3 / methanol / 24 h / 20 °C View Scheme
参考文献
Journal of Chemical Research - Part S, , # 4 p. 216 - 217
反应条件
1: NaBH4 / methanol / 2 h / 0 °C 2: 1.4 g / Ph3P, diethyl azodicarboxylate / toluene / Ambient temperature 3: 650 mg / aq. K2CO3 / methanol / 1 h / Ambient temperature 4: 1.) B2H6, 2.) NaOH, aq. H2O2 / multistep reaction: 1.) THF, 0 deg C, 4 h, 2.) overnight; hydroboration of androst-4-enes; stereochemical aspects View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 17 p. 2183 - 2188
反应条件
1: 1.4 g / Ph3P, diethyl azodicarboxylate / toluene / Ambient temperature 2: 650 mg / aq. K2CO3 / methanol / 1 h / Ambient temperature 3: 1.) B2H6, 2.) NaOH, aq. H2O2 / multistep reaction: 1.) THF, 0 deg C, 4 h, 2.) overnight; hydroboration of androst-4-enes; stereochemical aspects View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 17 p. 2183 - 2188
