1-氧杂螺[2.6]壬烷合成路线 （共 17 条）
反应条件
zinc(II) tetrahydroborate; silica gel in tetrahydrofuran 24 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ranu, Brindaban C.; Das, Asish R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 1881 - 1882
反应条件
zinc(II) tetrahydroborate; silica gel in tetrahydrofuran 24 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ranu, Brindaban C.; Das, Asish R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 1881 - 1882
反应条件
sodium hydride in diethylene glycol dimethyl ether
T=130°C; Corey reaction; 0.5 h;
参考文献
Butova, Ekaterina D.; Fokin, Andrey A.; Schreiner, Peter R.
Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5689 - 5696
反应条件
1: trimethyl-sulfonium iodide With sodium hydride in tetrahydrofuran; dimethyl sulfoxide
2: cycloheptanone in tetrahydrofuran; dimethyl sulfoxide
Corey-Chaykovsky reaction;
参考文献
Peng, Yu; Yang, Jin-Hui; Li, Wei-Dong Z.
Tetrahedron, 2006 , vol. 62, # 6 p. 1209 - 1215
反应条件
1: trimethyl-sulfonium iodide With n-butyllithium in tetrahydrofuran
T=0°C; 0.166667 h;
2: cycloheptanone in tetrahydrofuran
T=0 - 20°C; 1.5 h;
参考文献
Peng, Yu; Yang, Jin-Hui; Li, Wei-Dong Z.
Tetrahedron, 2006 , vol. 62, # 6 p. 1209 - 1215
反应条件
1: trimethylsulfonium triflate With n-butyllithium in tetrahydrofuran
2: cycloheptanone in tetrahydrofuran
Corey-Chaykovsky reaction;
参考文献
Peng, Yu; Yang, Jin-Hui; Li, Wei-Dong Z.
Tetrahedron, 2006 , vol. 62, # 6 p. 1209 - 1215
反应条件
1: trimethylsulphonium methyl sulphate With n-butyllithium in tetrahydrofuran
2: cycloheptanone in tetrahydrofuran
Corey-Chaykovsky reaction;
参考文献
Peng, Yu; Yang, Jin-Hui; Li, Wei-Dong Z.
Tetrahedron, 2006 , vol. 62, # 6 p. 1209 - 1215
参考文献
Peng, Yu; Yang, Jin-Hui; Li, Wei-Dong Z.
Tetrahedron, 2006 , vol. 62, # 6 p. 1209 - 1215
反应条件
2: 52 percent Chromat. / 80percent MCPBA / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
参考文献
Uemura, Sakae; Ohe, Kouichi; Sugita, Nobuyuki
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 6 p. 1697 - 1703
参考文献
Traynham; Pascual
Tetrahedron, 1959 , vol. 7, p. 165,167, 169
