2-苄基-1,2-二氢吲唑-3-酮合成路线 （共 14 条）
反应条件
1: With caesium carbonate in acetone 24 h; Reflux; 2: With potassium hydroxide in ethanol T=20°C; 1 h; 3: With hydrogenchloride in water
参考文献
Vega, Maria Celeste; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Escario, Jose Antonio; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 214 - 227
反应条件
potassium hydroxide in ethanol 4 h; Heating;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h 2: 66 percent / KOH / ethanol / 4 h / Heating View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 65 percent / pyridine / 2 h / Heating 2: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h 3: 66 percent / KOH / ethanol / 4 h / Heating View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 61 percent / KOH / 5 h / Heating 2: 95 percent / HBr / H2O / Heating View Scheme
参考文献
Kurth, Mark J.; Olmstead, Marilyn M.; Haddadin, Makhluf J.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1060 - 1062
反应条件
1.1: NaOH / H2O; methanol / Heating 1.2: HCl 2.1: 95 percent / HBr / H2O / Heating View Scheme
参考文献
Kurth, Mark J.; Olmstead, Marilyn M.; Haddadin, Makhluf J.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1060 - 1062
反应条件
in chloroform T=20°C;
参考文献
Kurth, Mark J.; Olmstead, Marilyn M.; Haddadin, Makhluf J.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1060 - 1062
反应条件
1: With sodium hydroxide in methanol; water Heating; 2: With hydrogenchloride
参考文献
Kurth, Mark J.; Olmstead, Marilyn M.; Haddadin, Makhluf J.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1060 - 1062
反应条件
in N,N-dimethyl-formamide T=100°C; 4 h;
参考文献
Aran, Vicente J.; Diez-Barra, Enrique; De La Hoz, Antonio; Sanchez-Verdu, Prado
Heterocycles, 1997 , vol. 45, # 1 p. 129 - 136
反应条件
1: With sodium hydroxide Heating; 2: With hydrogenchloride
参考文献
Kurth, Mark J.; Olmstead, Marilyn M.; Haddadin, Makhluf J.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1060 - 1062
