1-苄基-3-氨基吡咯烷合成路线 （共 19 条）
反应条件
ammonia; hydrogen; nickel in methanol P=760 Torr;
参考文献
Iwanami; Takashima; Hirata; Hasegawa; Usuda
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1224 - 1230
反应条件
palladium on charcoal in tetrahydrofuran; water
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 3 h; Heating;
参考文献
Jean, Ludovic; Baglin, Isabelle; Rouden, Jacques; Maddaluno, Jacques; Lasne, Marie-Claire
Tetrahedron Letters, 2001 , vol. 42, # 33 p. 5645 - 5649
反应条件
1: 72 percent / aq. NH4OH / 12 h 2: 75 percent / PhI(OAc)2 / H2O; acetonitrile / 1 h / 20 °C 3: 80 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5645 - 5649
反应条件
1: 75 percent / PhI(OAc)2 / H2O; acetonitrile / 1 h / 20 °C 2: 80 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5645 - 5649
反应条件
1: 70 percent / TFA; NaNO2 / aq. NaOH / 2 h / 0 - 80 °C 2: 80 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5645 - 5649
参考文献
Sugen, Inc.
Patent: US2003/130235 A1, 2003 ;
反应条件
sodium hydroxide in water; tert-butyl alcohol T=20°C; 12 h; Product distribution / selectivity;
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CRYSTALGENOMICS, INC.
Patent: WO2007/52938 A1, 2007 ;
Location in patent: Page/Page column 22-23 ;
WO 2007/052938 A1
参考文献
Warner-Lambert Company
Patent: US4885386 A1, 1989 ;
