1: 3-(phenylsulfonyl)-1(3H)-isobenzofuranone With lithium tert-butylate in tetrahydrofuran T=-60°C; 0.416667 h; 2: o-Cyano-cis-zimtsaeure-methylester in tetrahydrofuran T=-60 - 20°C; Further stages.;

1: 67 percent / TEA / Pd(OAc)2 / acetonitrile / 48 h / 100 °C 2: 75 percent / H2 / 10percent Pd/C, PtO2 / ethanol; various solvent(s) / 1) 50 deg C. vent, 2) 68 deg C, 2 h View Scheme