sodium hypobromide

sodium hypobromide

diisobutylaluminium hydride; cobalt(II) 2,4-pentanedionate in tetrahydrofuran; hexane T=-78 - 0°C; 2 h;

1: 96 percent / NaBH4 / methanol / 0.25 h 2: AcCl / ethanol / 0.5 h / 23 °C View Scheme

n-Butyl nitrite; phenyl silane; N,N'-bis(2-ethoxycarbonyl-3-oxobutylidene)ethylenediaminatocobalt(II) complex in tetrahydrofuran 19 h; Ambient temperature;

1: 1.) CuCN / 1.) THF, -23 deg C, 5 h, 2.) THF, from -23 deg C to RT, 1 h 2: 42 percent / m-chloroperbenzoic acid, disodium hydrogenphosphate / CH2Cl2 / 24 h / Ambient temperature 3: 100 percent / n-Bu4N+F- / tetrahydrofuran / 1 h / Ambient temperature View Scheme

2: 89 percent / MCPBA 3: 1) LiAlH4, 2) KH View Scheme