2-羟基-6-甲基苯甲醛合成路线 （共 24 条）
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Chemische Berichte, , vol. 62, p. 2595
反应条件
lithium aluminium tetrahydride; diethyl ether T=-10°C;
参考文献
Dunning; Dunning; Reid
Journal of the American Chemical Society, 1936 , vol. 58, p. 1565,1566
反应条件
bei der Kalischmelze;
参考文献
Chatterjea, J. N.; Singh, K. R. R. P.; Jha, I. S.; Prasad, Y.; Shaw, S. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 796 - 798
反应条件
boron tribromide in dichloromethane
T=0°C; 1.5 h;
参考文献
Pu; Scripko; Huang
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 12 p. 1183 - 1191
反应条件
sodium hydroxide in water
T=60°C; 8 h;
参考文献
Komiyama, Makoto; Hirai, Hidefumi
Journal of the American Chemical Society, 1983 , vol. 105, # 7 p. 2018 - 2021
反应条件
(C4H9)3N; tin(IV) chloride in toluene
T=100°C;
参考文献
Payne, Peter; Tyman, John H. P.; Mehet, Satinder K.; Ninagawa, Akira
Journal of Chemical Research, 2006 , # 6 p. 402 - 405
反应条件
1: With tetrabutyl ammonium fluoride
T=20°C; 3 h; Inert atmosphere;
2: With water
参考文献
Yoshioka, Eito; Miyabe, Hideto
Tetrahedron, 2012 , vol. 68, # 1 p. 179 - 189
反应条件
1: dipotassium peroxodisulfate
2: AlCl3, aluminium chloride / dichloromethane / 20 °C
View Scheme
参考文献
Pauloehrl, Thomas; Delaittre, Guillaume; Winkler, Volker; Welle, Alexander; Bruns, Michael; Boerner, Hans G.; Greiner, Alexandra M.; Bastmeyer, Martin; Barner-Kowollik, Christopher
Angewandte Chemie - International Edition, 2012 , vol. 51, # 4 p. 1071 - 1074
反应条件
1: 97 percent / DIBAL-H / hexane; diethyl ether / 0.17 h / -78 °C
2: 86 percent / MnO2 / benzene / 5 h / Heating
3: 41 percent / LiCl / dimethylformamide / 15 h / Heating
View Scheme
参考文献
Nakanishi, Tsutomu; Inatomi, Yuka; Murata, Hiroko; Iida, Naoki; Inada, Akira; Lang, Frank A; Murata, Jin
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1358 - 1361
反应条件
1.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / diethyl ether; hexane / 20 °C / Inert atmosphere
1.2: 12 h
2.1: hydrogenchloride; water / diethyl ether; hexane / 1 h / Inert atmosphere
View Scheme
参考文献
Coulter, Matthew M.; Kou, Kevin G. M.; Galligan, Baye; Dong, Vy M.
Journal of the American Chemical Society, 2010 , vol. 132, # 46 p. 16330 - 16333
