1: 2-methyl propanoic acid With lithium diisopropyl amide in tetrahydrofuran; hexanes T=-30°C; 2: 1,9-dichloro-5-oxanonane in tetrahydrofuran; hexanes T=-30 - 20°C; 2.5 h; Heating / reflux; 3: With hydrogenchloride in diethyl ether; water pH=2;

diisopropylamine in tetrahydrofuran

1: propionic acid With N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide in tetrahydrofuran 2: 1,9-dichloro-5-oxanonane in tetrahydrofuran Further stages.;