1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water / 20 °C / Inert atmosphere; Reflux 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; isopropyl alcohol / 0 - 20 °C / Inert atmosphere 3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere View Scheme

sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki-Miyaura cross-coupling; 6 h; Heating;

Bislt;trifluoromethylgt;mercury; copper in N,N-dimethyl acetamide T=140°C; 2 h;

1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water / 20 °C / Inert atmosphere; Reflux 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; isopropyl alcohol / 0 - 20 °C / Inert atmosphere 3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere 4: dihydrogen peroxide; sodium hydrogencarbonate / methanol / 20 °C / Inert atmosphere View Scheme