N-(叔丁氧羰基)对甲苯磺酰胺合成路线 （共 29 条）
反应条件
potassium hexamethylsilazane 1.) THF, -78 deg C, 2.) -78 deg C, 7 h; Yield given. Multistep reaction;
参考文献
Genet, Jean-Pierre; Hajicek, Josef; Bischoff, Laurent; Greck, Christine
Tetrahedron Letters, 1992 , vol. 33, # 19 p. 2677 - 2680
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C 1.2: 2 h / 20 °C 1.3: 20 °C 2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere View Scheme
参考文献
Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912
反应条件
1.1: 83 percent / PPh3; DIAD / tetrahydrofuran / 20 °C 2.1: Mg; MeOH / 0.5 h / 20 °C / sonication 3.1: n-BuLi / diethyl ether / 0 - 20 °C 3.2: diethyl ether / 1 h / 20 °C 4.1: AIBN; n-Bu3SnH / toluene / 0.5 h / -10 °C / Irradiation 4.2: 43 mg / aq. H2O2; KF; KHCO3 / tetrahydrofuran; methanol / 20 h / 20 °C View Scheme
参考文献
Blaszykowski, Christophe; Dhimane, Anne-Lise; Fensterbank, Louis; Malacria, Max
Organic letters, 2003 , vol. 5, # 8 p. 1341 - 1344
反应条件
potassium hexamethylsilazane
1.) THF, -78 deg C, 2.) -78 deg C, 10 min, then to -50 deg C, 1.75 h; Yield given. Multistep reaction;
参考文献
Genet, Jean-Pierre; Hajicek, Josef; Bischoff, Laurent; Greck, Christine
Tetrahedron Letters, 1992 , vol. 33, # 19 p. 2677 - 2680
反应条件
1: PPh3; DEAD / tetrahydrofuran / 0 - 20 °C
2: K2CO3 / methanol / 3 h / Heating
View Scheme
参考文献
Zheng, Huaiji; Huo, Xing; Zhao, Changgui; Jing, Peng; Yang, Juan; Fang, Bowen; She, Xuegong
Organic Letters, 2011 , vol. 13, # 24 p. 6448 - 6451
反应条件
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
View Scheme
参考文献
Zheng, Huaiji; Huo, Xing; Zhao, Changgui; Jing, Peng; Yang, Juan; Fang, Bowen; She, Xuegong
Organic Letters, 2011 , vol. 13, # 24 p. 6448 - 6451
反应条件
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 °C / |Inert atmosphere
2: trifluoroacetic acid / 1 h
View Scheme
参考文献
Garzon, Cecile; Attolini, Mireille; Maffei, Michel
European Journal of Organic Chemistry, 2013 , # 18 p. 3653 - 3657
反应条件
1: PPh3; DEAD / tetrahydrofuran / 0 - 20 °C
2: K2CO3 / methanol / 3 h / Heating
View Scheme
参考文献
Padwa, Albert; Dimitroff, Martin; Waterson, Alex G.; Wu, Tianhua
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 3986 - 3997
反应条件
1: 86 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature
2: 82 percent / sodium naphthalenide / 1,2-dimethoxy-ethane / Ambient temperature
View Scheme
参考文献
Henry, James R.; Marcin, Lawrence R.; McIntosh, Matthias C.; Scola, Paul M.; Harris, G. Davis; Weinreb, Steven M.
Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5709 - 5712
反应条件
1: PPh3; DEAD / tetrahydrofuran / 0 - 20 °C
2: K2CO3 / methanol / 3 h / Heating
View Scheme
参考文献
Marion, Frederic; Coulomb, Julien; Courillon, Christine; Fensterbank, Louis; Malacria, Max
Organic Letters, 2004 , vol. 6, # 9 p. 1509 - 1511
