1-乙基苯并(cd)吲哚-2(1H)-酮合成路线 （共 7 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 3 h;
参考文献
Zhang, Yan; Xue, Xiaoqian; Jin, Xiangyu; Song, Yu; Li, Jing; Luo, Xiaoyu; Song, Ming; Yan, Weiqun; Song, Hongrui; Xu, Yong
European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 431 - 441
反应条件
in aqueous potassium hydroxide; acetone
参考文献
EASTMAN KODAK COMPANY, (a New Jersey corporation)
Patent: EP286402 A3, 1991 ;
反应条件
sodium hydroxide; butyltrialkylammonium nitrate T=85°C; Alkylation; 0.25 h;
参考文献
Anikin; Krasnova; Kupriyan
Russian Journal of Applied Chemistry, 2000 , vol. 73, # 3 p. 486 - 489
反应条件
1.1: hydroxylamine hydrochloride; pyridine / 1 h / 95 °C 2.1: 1 h / 95 °C 3.1: sodium hydroxide / ethanol; water / 3 h / |Reflux 3.2: 0.5 h / 20 °C 4.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C View Scheme
参考文献
Zhang, Yan; Xue, Xiaoqian; Jin, Xiangyu; Song, Yu; Li, Jing; Luo, Xiaoyu; Song, Ming; Yan, Weiqun; Song, Hongrui; Xu, Yong
European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 431 - 441
反应条件
1.1: sodium hydroxide / ethanol; water / 3 h / |Reflux 1.2: 0.5 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C View Scheme
参考文献
Zhang, Yan; Xue, Xiaoqian; Jin, Xiangyu; Song, Yu; Li, Jing; Luo, Xiaoyu; Song, Ming; Yan, Weiqun; Song, Hongrui; Xu, Yong
European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 431 - 441
反应条件
1.1: 1 h / 95 °C 2.1: sodium hydroxide / ethanol; water / 3 h / |Reflux 2.2: 0.5 h / 20 °C 3.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C View Scheme
参考文献
Zhang, Yan; Xue, Xiaoqian; Jin, Xiangyu; Song, Yu; Li, Jing; Luo, Xiaoyu; Song, Ming; Yan, Weiqun; Song, Hongrui; Xu, Yong
European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 431 - 441
反应条件
copper; copper(l) chloride T=165 - 170°C; unter Druck;
参考文献
I.G.Farbenind.
Patent: FR778254 , 1934 ;
