1: With n-butyllithium; isopropylmagnesium chloride in tetrahydrofuran; hexane T=-2 - 0°C; 0.75 h; Inert atmosphere; 2: With iodine in tetrahydrofuran; hexane T=0 - 20°C; Inert atmosphere;

iodine cloride in tetrachloromethane; dichloromethane 48 h; Yield given;

1: With (2,2,6,6-tetramethylpiperidinyl)MgCl*LiCl in tetrahydrofuran T=0°C; Inert atmosphere; 2: With iodine in tetrahydrofuran T=-30 - 25°C; Inert atmosphere; regioselective reaction;

1: 2-bromo-pyridine With nBu4ZnLi2*TMEDA in toluene T=20°C; 1 h; Inert atmosphere; 2: 2-iodo-6-methoxypyridine With bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine in toluene 12 h; Inert atmosphereReflux;