5-(氯甲基)-3-苯基-1,2,4-氧二唑合成路线 （共 16 条）
反应条件
sulfuric acid; nitric acid T=-5 - 0°C;
参考文献
Palazzo,G.; Corsi,G.
Gazzetta Chimica Italiana, 1963 , vol. 93, p. 1196 - 1205
反应条件
potassium carbonate in acetonitrile
0.5 h; Reflux;
参考文献
Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805
反应条件
1: K2CO3 / dimethylsulfoxide
2: aq. K2CO3 / methanol / Heating
3: SOCl2 / dimethylformamide / Heating
4: benzene
View Scheme
参考文献
Jaunin,R.
Helvetica Chimica Acta, 1966 , vol. 49, p. 412 - 419
反应条件
sodium acetate
T=140°C;
参考文献
Palazzo,G.; Silvestrini,B.
Bollettino Chimico Farmaceutico, 1962 , vol. 101, p. 251 - 258
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane in acetic acid
Heating;
参考文献
Palazzo,G.; Silvestrini,B.
Bollettino Chimico Farmaceutico, 1962 , vol. 101, p. 251 - 258
参考文献
Palazzo,G. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, # 2 p. 351 - 367
