2-甲基-2H-吲唑-3-甲酰氯合成路线 （共 4 条）
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane 1 h;
参考文献
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
Patent: WO2008/61688 A1, 2008 ;
Location in patent: Page/Page column 21 ;
WO 2008/061688 A1
反应条件
1: 100 percent / 1N NaOH / tetrahydrofuran / Ambient temperature 2: SOCl2 / CHCl3 / Heating View Scheme
参考文献
Vishnu, Eda V.R.; Joseph, Suju; Srinivasana, Abayee K.; Gania, Ramesh S.; Reddy, Govindabur R.; Rao, Patakokila V.; Dahanukara, Vilas H.; Ramanatham, Josyula; Devanna, Nayakanti
Letters in Organic Chemistry, 2011 , vol. 8, # 10 p. 722 - 727
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 55 °C 2: sodium hydroxide / water / 1 h / 65 - 70 °C 3: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 3 h / Reflux View Scheme
参考文献
Vishnu, Eda V.R.; Joseph, Suju; Srinivasana, Abayee K.; Gania, Ramesh S.; Reddy, Govindabur R.; Rao, Patakokila V.; Dahanukara, Vilas H.; Ramanatham, Josyula; Devanna, Nayakanti
Letters in Organic Chemistry, 2011 , vol. 8, # 10 p. 722 - 727
反应条件
triethylamine in dichloromethane 2 h; Yield given;
参考文献
Bermudez, Jose; Fake, Charles S.; Joiner, Graham F.; Joiner, Karen A.; King, Frank D.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1924 - 1929
