2-(羟基苯基甲基)-丙烯酸甲酯合成路线 （共 26 条）
反应条件
1: lithium bromide / Acidic conditions 2: water; triphenylphosphine; lithium hydroxide hydrate / acetonitrile / 0.67 h / 100 °C / Microwave irradiation View Scheme
参考文献
Meier, Lidiane; Ferreira, Misael; Sa, Marcus M.
Heteroatom Chemistry, 2012 , vol. 23, # 2 p. 179 - 186
反应条件
1: 1H-imidazole; dimethyl sulfoxide / 20 °C / Inert atmosphere 2: water; lithium hydroxide hydrate / acetonitrile / 4 h / 50 - 60 °C 3: triethylamine / acetone / 0.08 h / 0 °C 4: sodium azide / acetone / 2 h / 20 °C 5: toluene / 2 h / Reflux; Inert atmosphere 6: water / 2 h / Reflux 7: tetrabutyl ammonium fluoride / methanol / 2 h / 20 °C View Scheme
参考文献
Amarante, Giovanni W.; Cavallaro, Mayra; Coelho, Fernando
Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 8 p. 1568 - 1584
反应条件
tetrabutylammomium bromide; sodium formate; sodium hydrogencarbonate; Pd-benzothiazole carbene T=130°C; 20 h;
参考文献
Calo, Vincenzo; Nacci, Angelo; Lopez, Luigi; Napola, Annalisa
Tetrahedron Letters, 2001 , vol. 42, # 28 p. 4701 - 4703
反应条件
triethylamine; triphenylphosphine; palladium diacetate T=100°C; Arylation; Heck; 7 h;
参考文献
Synthetic Communications, , vol. 28, # 12 p. 2311 - 2316
反应条件
1: lithium bromide / Acidic conditions 2: acetonitrile / 28 h / 25 °C 3: water; sodium hydrogencarbonate / 0.33 h / 100 - 105 °C / Microwave irradiation View Scheme
参考文献
Meier, Lidiane; Ferreira, Misael; Sa, Marcus M.
Heteroatom Chemistry, 2012 , vol. 23, # 2 p. 179 - 186
反应条件
1.1: pyridine / dichloromethane / 3 h / 0 - 20 °C 2.1: methanol; ammonia / 1 h / 20 °C 3.1: iodine / chloroform / 0.08 h 3.2: 0.5 h / 20 °C View Scheme
参考文献
Batchu, Harikrishna; Bhattacharyya, Soumya; Batra, Sanjay
Organic Letters, 2012 , vol. 14, # 24 p. 6330 - 6333
反应条件
iodosylbenzene; potassium bromide in water T=20°C; 6 h;
参考文献
Das, Biswanath; Holla, Harish; Venkateswarlu, Katta; Majhi, Anjoy
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8895 - 8897
反应条件
sodium hypochlorite in acetonitrile 1.25 h; Ambient temperatureother methyl 3-hydroxy-2-methylenealkanoates or 3-aryl-3-hydroxy-2-methylenepropanenitriles;
参考文献
Foucaud, Andre; Rouille, Eliane de
Synthesis, 1990 , # 9 p. 787 - 789
反应条件
sulfuric acid; water; hydrogen bromide; acetic acid T=20°C; 16 h; Inert atmosphere;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Dhanorkar, Ritesh J.
Tetrahedron, 2010 , vol. 66, # 20 p. 3623 - 3632
反应条件
sodium hydride in tetrahydrofuran T=67°C;
参考文献
Chen, Chung-Yi; Chang, Meng-Yang; Hsu, Ru-Ting; Chen, Shui-Tein; Chang, Nein-Chen
Tetrahedron Letters, 2003 , vol. 44, # 47 p. 8627 - 8630
