3-(三氟甲基)苯甲酰胺合成路线 （共 11 条）
反应条件
1: With caesium carbonate in pyrrolidin-2-one T=130°C; 2 h; Sealed vessel; 2: With methanol in pyrrolidin-2-one; dichloromethane T=20°C; Filtering through Celite pad;
参考文献
Sahnoun, Sophian; Messaoudi, Samir; Peyrat, Jean-Francois; Brion, Jean-Daniel; Alami, Mouad
Tetrahedron Letters, 2012 , vol. 53, # 23 p. 2860 - 2863
反应条件
4-(N,N-dimethlyamino)pyridine; bis-triphenylphosphine-palladium(II) chloride; carbon monoxide in 1,4-dioxane T=120°C; P=3750.38 Torr; 18 h;
参考文献
Schnyder, Anita; Indolese, Adriano F.
Journal of Organic Chemistry, 2002 , vol. 67, # 2 p. 594 - 597
反应条件
2,4,6-trimethyl-pyridine; copper diacetate in N,N-dimethyl acetamide T=25°C; P=760.051 Torr; 16 h; Inert atmosphere;
参考文献
Xu, Jun; Luo, Dong-Fen; Xiao, Bin; Liu, Zhao-Jing; Gong, Tian-Jun; Fu, Yao; Liu, Lei
Chemical Communications, 2011 , vol. 47, # 14 p. 4300 - 4302
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in 1,4-dioxane T=120°C; P=3750.38 Torr; 8 h;
参考文献
Journal of Organic Chemistry, , vol. 67, # 2 p. 594 - 597
反应条件
4-(N,N-dimethlyamino)pyridine; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane T=120°C; P=3750.38 Torr; 2 h; Further byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 66, # 12 p. 4311 - 4315
反应条件
ammonium hydroxide T=20°C; 0.5 h;
参考文献
Kakuta, Hiroki; Zheng, Xiaoxia; Oda, Hiroyuki; Harada, Shun; Sugimoto, Yukio; Sasaki, Kenji; Tai, Akihiro
Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2400 - 2411
反应条件
[η5-pentamethylcyclopentadienyl*Ir(H2O)3][OTf ]2 in water T=110°C; 12 h; Schlenk technique;
参考文献
Sun, Chunlou; Qu, Panpan; Li, Feng
Catalysis Science and Technology, 2014 , vol. 4, # 4 p. 988 - 996
反应条件
4-(N,N-dimethlyamino)pyridine; formamide; triphenylphosphine; palladium diacetate T=120°C; P=3750.38 Torr; 18 h; Product distribution; Further Variations:TemperaturesPressuresReagentsSolventscatalysts, reaction times;
参考文献
Schnyder; Beller; Mehltretter; Nsenda; Studer; Indolese
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4311 - 4315
反应条件
formamide; triphenylphosphine in water
