1,5-二氧杂螺[5.5]十一烷合成路线 （共 12 条）
反应条件
indium trifluoromethanesulfonate T=20°C; 0.5 h; Neat (no solvent);
参考文献
Smith, Brendan M.; Kubczyk, Tomasz M.; Graham, Andrew E.
Tetrahedron, 2012 , vol. 68, # 38 p. 7775 - 7781
反应条件
orthoformic acid triethyl ester; zirconium tetrachloride in dichloromethane 0.166667 h; Ambient temperature;
参考文献
Firouzabadi, Habib; Iranpoor, Nasser; Karimi, Babak
Synlett, 1999 , # 3 p. 321 - 323
反应条件
N-halosuccinimide in dichloromethane T=20°C; 0.0833333 h;
参考文献
Karimi, Babak; Seradj, Hassan; Maleki, Jafar
Tetrahedron, 2002 , vol. 58, # 22 p. 4513 - 4516
反应条件
acetic acid in acetonitrile-D3; water
参考文献
Deslongchamps, Pierre; Dory, Yves L.; Li, Shigui
Helvetica Chimica Acta, 1996 , vol. 79, # 1 p. 41 - 50
反应条件
toluene-4-sulfonic acid Heating;
参考文献
Grindley, T. Bruce; Cote, Christian J. P.; Wickramage, Chandra
Carbohydrate Research, 1985 , vol. 140, p. 215 - 238
反应条件
1: 1.) AcOH; 2.) triethylamine / 1.) benzene, 34 h, room temp.; 2: 1.) NBS; 2.) triethylamine / 1.) CD3CN, MeOH, 10 min, NMR tube; 2.) CD3CN, MeOH, NMR tube View Scheme
参考文献
Deslongchamps, Pierre; Dory, Yves L.; Li, Shigui
Helvetica Chimica Acta, 1996 , vol. 79, # 1 p. 41 - 50
反应条件
N-bromosuccinmide; triethylamine 1.) CD3CN, MeOH, 10 min, NMR tube; 2.) CD3CN, MeOH, NMR tube; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Deslongchamps, Pierre; Dory, Yves L.; Li, Shigui
Helvetica Chimica Acta, 1996 , vol. 79, # 1 p. 41 - 50
反应条件
1: 82 percent / (i-Pr)3Al / toluene; CH2Cl2 / -78 deg C to room temp., then 12 h 2: 40 percent Spectr. / AcOH / H2O; CD3CN View Scheme
参考文献
Deslongchamps, Pierre; Dory, Yves L.; Li, Shigui
Helvetica Chimica Acta, 1996 , vol. 79, # 1 p. 41 - 50
反应条件
lithium trifluoromethane sulfonate T=90°C; 1 h;
参考文献
Naik, Sarala; Gopinath, Rangam; Goswami, Mousumi; Patel, Bhisma K.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 11 p. 1670 - 1677
反应条件
methyl iodide in toluene T=80 - 90°C; 12 h; Title compound not separated from byproducts.;
参考文献
Iwata, Arihiro; Tang, Heqing; Kunai, Atsutaka; Ohshita, Joji; Yamamoto, Yasushi; Matui, Chinami
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5170 - 5175
