1,7-二氧螺环-[5,5]十一烷合成路线 （共 40 条）
反应条件
1: 1.) 3-chloroperbenzoic acid, 2.) 10-camphorsulfonic acid / 1.) benzene, RT, 2 h, 2.) benzene, RT, 15 min 2: 97 percent / H2, Na2HPOP4 / 5percent Pd/C / methanol / 2 h 3: 85 percent / zinc triflate / CH2Cl2 / 16 h / Heating 4: 78 percent / H2 / W-2 Raney Ni / ethanol / 36 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 1901
反应条件
1: 97 percent / H2, Na2HPOP4 / 5percent Pd/C / methanol / 2 h 2: 85 percent / zinc triflate / CH2Cl2 / 16 h / Heating 3: 78 percent / H2 / W-2 Raney Ni / ethanol / 36 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 1901
反应条件
1: 86 percent / NaBH4, 5percent aq. NaOH / methanol / 6 h / Ambient temperature 2: 1.) 3-chloroperbenzoic acid, 2.) 10-camphorsulfonic acid / 1.) benzene, RT, 2 h, 2.) benzene, RT, 15 min 3: 97 percent / H2, Na2HPOP4 / 5percent Pd/C / methanol / 2 h 4: 85 percent / zinc triflate / CH2Cl2 / 16 h / Heating 5: 78 percent / H2 / W-2 Raney Ni / ethanol / 36 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 1901
反应条件
amberlite IR 120 A; magnesium sulfate in tetrahydrofuran; hexane 48 h; Heating;
参考文献
Enders; Dahmen; Dederichs; Gatzweiler; Weuster
Synthesis, 1990 , # 11 p. 1013 - 1019
反应条件
n-butyllithium in tetrahydrofuran T=-78°C;
参考文献
Tetrahedron Letters, , vol. 26, # 4 p. 535 - 538
反应条件
1: 82 percent / CSA / CH2Cl2 / 20 °C 2: 93 percent / H2 / Pd/C / ethyl acetate / 6 h / 25 °C / 760 Torr View Scheme
参考文献
Heterocycles, , vol. 67, # 1 p. 85 - 88
反应条件
1: 86 percent / H2 / Raney Nickel / ethanol / 4 h / 20 °C 2: HgO; I2 / cyclohexane / 16 h / Heating View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 8 p. 1145 - 1154
反应条件
Bactrocera cacuminate; oxygen; H218O; nitrogen 120 h; Further byproducts.;
参考文献
Journal of the American Chemical Society, , vol. 124, # 26 p. 7666 - 7667
反应条件
1.1: n-butyllithium; HMPA / tetrahydrofuran; hexane / 1.25 h / -78 - 20 °C / Inert atmosphere 1.2: 18 h / 20 °C / Inert atmosphere 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere 3.1: water; Hg(OTf)2 / acetonitrile / 0.17 h / 20 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 13, # 12 p. 3178 - 3181
反应条件
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere 2: water; Hg(OTf)2 / acetonitrile / 0.17 h / 20 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 13, # 12 p. 3178 - 3181
