2-三正丁基甲锡烷基吡啶合成路线 （共 97 条）
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
Stille coupling reaction; 24 h; RefluxInert atmosphere;
参考文献
Song, Guoyong; Li, Yongxin; Chen, Shanshan; Li, Xingwei
Chemical Communications, 2008 , # 30 p. 3558 - 3560
反应条件
1.1: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 3 h / 120 °C / Inert atmosphere
2.1: water; hydrogen bromide / 3 h / 110 °C
2.2: pH 11 / Cooling with ice
3.1: pyridine; copper diacetate / N,N-dimethyl-formamide / 16 h
4.1: N-bromosuccinmide / N,N-dimethyl-formamide / 4 h / 20 °C
View Scheme
参考文献
McElhinny Jr., Charles J.; Carroll; Lewin, Anita H.
Synthesis, 2012 , vol. 44, # 1 art. no. M92511SS, p. 57 - 62
反应条件
1: With tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=120°C; Stille coupling; 3 h; Inert atmosphere;
2: With sodium hydrogencarbonate in diethyl ether; water
参考文献
McElhinny Jr., Charles J.; Carroll; Lewin, Anita H.
Synthesis, 2012 , vol. 44, # 1 art. no. M92511SS, p. 57 - 62
反应条件
1: With lithium chloride; bis-triphenylphosphine-palladium(II) chloride in toluene
18 h; Heating;
2: With NAF in water; toluene
T=20°C; 0.5 h;
参考文献
Tomon, Takashi; Koizumi, Take-Aki; Tanaka, Koji
European Journal of Inorganic Chemistry, 2005 , # 2 p. 285 - 293
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
T=110°C; 48 h;
参考文献
Hyun, Soo Lee; Schultz, Peter G.
Journal of the American Chemical Society, 2008 , vol. 130, # 40 p. 13194 - 13195
反应条件
bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=110°C; Stille cross-coupling; 18 h;
参考文献
Verniest, Guido; Wang, Xingpo; De Kimpe, Norbert; Padwa, Albert
Journal of Organic Chemistry, 2010 , vol. 75, # 2 p. 424 - 433
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
Stille-type cross-coupling; 48 h; Heating;
参考文献
Heller, Marcel; Schubert, Ulrich S.
Journal of Organic Chemistry, 2002 , vol. 67, # 23 p. 8269 - 8272
