6-甲基-2-氧代-1,2,3,4-四氢嘧啶-5-羧酸乙酯合成路线 （共 14 条）
反应条件
Cl7Fe2(1-)*C6H9N2O2(1+); C8H15N2(1+)*C4H12B(1-) T=80°C; Biginelli Pyrimidone Synthesis; 2 h;
参考文献
Ramos, Luciana M.; Guido, Bruna C.; Nobrega, Catharine C.; Correa, Jose R.; Silva, Rafael G.; De Oliveira, Heibbe C. B.; Gomes, Alexandre F.; Gozzo, Fabio C.; Neto, Brenno A. D.
Chemistry - A European Journal, 2013 , vol. 19, # 13 p. 4156 - 4168
反应条件
iodine; magnesium in methanol T=50°C; 30 h; chemoselective reaction;
参考文献
Singh, Kamaljit; Singh, Kawaljit
Tetrahedron Letters, 2009 , vol. 50, # 19 p. 2219 - 2221
反应条件
trifluoroacetic acid in acetonitrile Condensation; Biginelli reaction; 1 h; Heating;
参考文献
Singh, Kamaljit; Singh, Jasbir; Deb, Prasant K.; Singh, Harjit
Tetrahedron, 1999 , vol. 55, # 44 p. 12873 - 12880
反应条件
piperidine; urea 0.666667 h; Heating;
参考文献
Bakibaev, A. A.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4 p. 736 - 740
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 854 - 859
反应条件
ethanol T=120 - 125°C;
参考文献
Boehme; Mundlos
Chemische Berichte, 1953 , vol. 86, p. 1414,1417
反应条件
piperidine 0.666667 h; Heating;
参考文献
Bakibaev, A. A.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4 p. 736 - 740
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 854 - 859
参考文献
Boehme; Mundlos
Chemische Berichte, 1953 , vol. 86, p. 1414,1417
反应条件
1: pyridinium chlorochromate 2: trichlorophosphate / 0.5 h / 105 °C 3: ethanol / 80 °C View Scheme
参考文献
Singh, Kamaljit; Singh, Kawaljit; Wan, Baojie; Franzblau, Scott; Chibale, Kelly; Balzarini, Jan
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2290 - 2294
反应条件
1: pyridinium chlorochromate 2: trichlorophosphate / 0.5 h / 105 °C 3: ammonia / tetrahydrofuran / 0.75 h / 20 °C View Scheme
参考文献
Singh, Kamaljit; Singh, Kawaljit; Wan, Baojie; Franzblau, Scott; Chibale, Kelly; Balzarini, Jan
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2290 - 2294
反应条件
pyridinium chlorochromate in dichloromethane T=20°C; 20 h;
参考文献
Singh, Kamaljit; Singh, Kawaljit
Australian Journal of Chemistry, 2008 , vol. 61, # 11 p. 910 - 913
