1-(三甲基硅烷基乙炔基)环己醇合成路线 （共 16 条）
反应条件
NiCl2((PPh3)P)2; water-d2; iso-propylmagnesium bromide
1.) ether, benzene, reflux, 15 min, 2.) 80 deg C, 72 h; Yield given. Multistep reaction;
参考文献
Wenkert, Ernest; Leftin, Michael H.; Michelotti, Enrique L.
Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1122 - 1124
反应条件
triethylamine in diethyl ether
T=-20°C;
参考文献
Cutting, Ian; Parsons, Philip J.
Tetrahedron Letters, 1983 , vol. 24, # 41 p. 4463 - 4464
反应条件
1: 66 percent / Et3N / diethyl ether / -20 °C
2: 68 percent / LiAlH4 / diethyl ether / -50 °C
View Scheme
参考文献
Cutting, Ian; Parsons, Philip J.
Tetrahedron Letters, 1983 , vol. 24, # 41 p. 4463 - 4464
反应条件
1: 66 percent / Et3N / diethyl ether / -20 °C
2: 56 percent / diethyl ether / Heating
View Scheme
参考文献
Cutting, Ian; Parsons, Philip J.
Tetrahedron Letters, 1983 , vol. 24, # 41 p. 4463 - 4464
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 20 °C / Inert atmosphere
2: [AuCl(PPh3)]; F5Sb*AgF; water / 1,4-dioxane / 24 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ghosh, Nayan; Nayak, Sanatan; Sahoo, Akhila K.
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 500 - 511
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 20 °C / Inert atmosphere
2: [AuCl(PPh3)]; F5Sb*AgF; water / 1,4-dioxane / 24 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ghosh, Nayan; Nayak, Sanatan; Sahoo, Akhila K.
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 500 - 511
