2,3,4,9-四氢-1H-吡啶并[3,4-b]吲哚-1-酮合成路线 （共 43 条）
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Bailey, A. Sydney; Vandrevala, Marazban H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1512 - 1515
反应条件
sodium hydride; toluene anschliessend Erhitzen mit CH3I;
参考文献
Abramovitch
Journal of the Chemical Society, 1956 , p. 4593,4597
反应条件
1: 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one With hydrogenchloride in chloroform 2: With trichlorophosphate T=40°C; 2 h; 3: 2-amino-benzoic acid methyl ester in tetrahydrofuran T=20°C; 12 h;
参考文献
Lee, Eung Seok; Park, Jae-Gyu; Jahng, Yurngdong
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1883 - 1886
反应条件
thionyl chloride in benzene
参考文献
Jahng, Katherine Chae; Kim, Seung Ill; Kim, Dong Hyeon; Seo, Chang Seob; Son, Jong-Keun; Lee, Seung Ho; Lee, Eung Seok; Jahng, Yurngdong
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 4 p. 607 - 609
反应条件
1: 49 percent / Et3N / benzene 2: 71 percent / tributylphosphine / benzene / 2 h / 60 °C View Scheme
参考文献
Eguchi, Shoji; Takeuchi, Hisato; Matsushita, Yuji
Heterocycles, 1992 , vol. 33, # 1 p. 153 - 156
反应条件
1: KOH / ethanol / 6 h / Heating 2: 10percent aq. HCl / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 25 p. 4307 - 4316
反应条件
trichlorophosphate in toluene 1 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 9 p. 1991 - 1994
反应条件
1: aqueous NaOH; acetone 2: aq.-ethanolic KOH 3: aqueous HCl View Scheme
参考文献
Abramovitch
Journal of the Chemical Society, 1956 , p. 4593,4597
反应条件
1: With dimethylphosphoryl azide; triethylamine in toluene
T=90°C; Curtius Rearrangement; 1.5 h; Inert atmosphere;
2: With boron trifluoride diethyl etherate in toluene
T=0 - 20°C; Curtius Rearrangement; 16 h; Inert atmosphere;
参考文献
Unsworth, William P.; Kitsiou, Christiana; Taylor, Richard J. K.
Organic Letters, 2013 , vol. 15, # 13 p. 3302 - 3305
反应条件
formic acid
T=100°C; 0.5 h;
参考文献
Bailey, A. Sydney; Vandrevala, Marazban H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1512 - 1515
