3,3-双(甲硫基)-2-氰基丙烯酸乙酯合成路线 （共 33 条）
反应条件
potassium carbonate; tetrabutylammomium bromide in benzene T=60°C; 3 h;
参考文献
Gazzetta Chimica Italiana, , vol. 125, # 3 p. 115 - 118
反应条件
1: cyanoacetic acid ethyl ester With potassium hydroxide in acetonitrile T=20°C; 1 h; Inert atmosphere; 2: carbon disulfide in acetonitrile T=-5°C; 1 h; Inert atmosphere; 3: dimethyl sulfate in acetonitrile T=0 - 20°C; 6 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 8, # 15 p. 3394 - 3397
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 8 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 24 p. 6890 - 6892
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 4 p. 1022 - 1024
反应条件
1: 95 percent / potassium hydroxide / dioxane 2: 28 percent / HCl / H2O; CH2Cl2 / 16 h 3: 1.) methanolic sodium methoxide / 1.) dioxane; 2.) room temperature, 2 h. View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1038 - 1044
反应条件
in acetonitrile T=0 - 20°C;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 58, # 5 p. 2730 - 2735
反应条件
diethyl ether Mehrtaegiges Erwaermen des Reaktionsgemisches mit Methyljodid.;
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 17, p. 362 - 376
反应条件
sodium methylate 1.) dioxane; 2.) room temperature, 2 h.; Yield given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1038 - 1044
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1187 - 1196
