4-硝基苯酚三氟甲基磺酸酯合成路线 （共 131 条）
反应条件
20°C; excess of RSO2F lose at 50°C;
参考文献
US3346612 , ;
C.A., , vol. 68, p. 21698
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene 2: 10 palladium on activated charcoal; hydrogen / ethanol View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in tetrahydrofuran; N,N-dimethyl-formamide T=80°C; 22 h;
参考文献
Curran, Dennis P.; Hoshino, Masahide
Journal of Organic Chemistry, 1996 , vol. 61, # 19 p. 6480 - 6481
反应条件
7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL in acetonitrile T=80°C; Esterification;
参考文献
Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping
Tetrahedron Letters, 1999 , vol. 40, # 42 p. 7469 - 7472
反应条件
1: DIPEA / Pd(PPh3)2Cl2; CuI / dimethylformamide / 48 h / 45 °C 2: aq. NaOH / diethyl ether; methanol / 18 h 3: CuSO4; sodium ascorbate; KHCO3 / 2-methyl-propan-2-ol; H2O / 24 h / 50 °C 4: aq. NaOH / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Soellner, Matthew B.; Rawls, Katherine A.; Grundner, Christoph; Alber, Tom; Ellman, Jonathan A.
Journal of the American Chemical Society, 2007 , vol. 129, # 31 p. 9613 - 9615
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene 2: 10 palladium on activated charcoal; hydrogen / ethanol View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
[Cp*Ru(CH3CN)3][SO3CF3]; lithium bromide T=100°C; 12 h; Inert atmosphere;
参考文献
Imazaki, Yusuke; Shirakawa, Eiji; Ueno, Ryota; Hayashi, Tamio
Journal of the American Chemical Society, 2012 , vol. 134, # 36 p. 14760 - 14763
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene 2: 10 palladium on activated charcoal; hydrogen / ethanol View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene 2: 10 palladium on activated charcoal; hydrogen / ethanol View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
bis (triortho-tolylphosphine)palladium(II) chloride; pyridine-3-carboxamide; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl T=150°C; 16 h; Inert atmosphere;
参考文献
Romero; Harrak; Basset; Orue; Pujol
Tetrahedron, 2009 , vol. 65, # 10 p. 1951 - 1956
