3alpha,17,21-三羟基-5beta-孕甾烷-11,20-二酮 21-乙酸酯合成路线 （共 8 条）
反应条件
bromine folgende Umsetzung mit Kaliumacetat;
参考文献
Joly et al.
Bulletin de la Societe Chimique de France, 1957 , p. 330
Full Text Show Details
Hershberg et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3849,3851
反应条件
1: 7.4 g / H2 / palladium on calcium carbonate / pyridine / 12 h 2: 1.7 g / H2 / Raney nickel (W-2) / dioxane / 10 h 3: 390 mg / imidazole / pyridine; dimethylformamide / 1 h / Ambient temperature 4: 400 mg / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature 5: 380 mg / 30 percent H2SO4 / acetone / 0.5 h / Ambient temperature View Scheme
参考文献
Hosoda; Saito; Ito; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 6 p. 2110 - 2118
反应条件
1: 1.7 g / H2 / Raney nickel (W-2) / dioxane / 10 h 2: 390 mg / imidazole / pyridine; dimethylformamide / 1 h / Ambient temperature 3: 400 mg / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature 4: 380 mg / 30 percent H2SO4 / acetone / 0.5 h / Ambient temperature View Scheme
参考文献
Hosoda; Saito; Ito; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 6 p. 2110 - 2118
反应条件
sulfuric acid in acetone 0.5 h; Ambient temperature;
参考文献
Hosoda; Saito; Ito; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 6 p. 2110 - 2118
反应条件
1: 390 mg / imidazole / pyridine; dimethylformamide / 1 h / Ambient temperature 2: 400 mg / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature 3: 380 mg / 30 percent H2SO4 / acetone / 0.5 h / Ambient temperature View Scheme
参考文献
Hosoda; Saito; Ito; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 6 p. 2110 - 2118
反应条件
1: 400 mg / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature 2: 380 mg / 30 percent H2SO4 / acetone / 0.5 h / Ambient temperature View Scheme
参考文献
Hosoda; Saito; Ito; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 6 p. 2110 - 2118
反应条件
chloroform; hydrogen bromide folgende Umsetzung mit Raney-Nickel in Aethanol;
参考文献
Glidden Co.
Patent: US2752339 , 1950 ;
参考文献
Hershberg et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3849,3851
