2,3,4,5-四氯-6-氟吡啶合成路线 （共 7 条）
反应条件
in gas Evaporation of FC5H4N and solvent CCl4 between 300 and 350 °C, chlorination at 695 °C (dwell time 17.3 s).;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
catalyst: chromium oxide fluoride in gas 560-580 °C (1 h, contact time 4-6 h);;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
in sulfolane Fluorination at 150 °C (4.5 h).;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
in sulfolane Fluorination at 215 °C (4.5 h) in sulfolane (containing 0.6 vol-percent H2O) gives a turnover of 95.8 percent, product ratio 2-F-C5Cl4N/3-Cl-C5F4N/3,5-Cl2-C5F3N = 3/6/91;;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
Catalyst M-Chromium oxide T=520°C;
参考文献
Weigert, F. J.
Journal of Fluorine Chemistry, 1991 , vol. 53, # 1 p. 33 - 42
参考文献
The Dow Chemical Company
Patent: US4746744 A1, 1988 ;
反应条件
in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dimethyl sulfoxide
参考文献
The Dow Chemical Company
Patent: US4766219 A1, 1988 ;
