(Z)-5-(丙烯-1-基)-1,3-苯并二氧戊环合成路线 （共 18 条）
反应条件
1: 83.3 percent / H2SO4 / 18 h / Heating 2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) THF, -78 deg C -> RT 3: 5.9 percent / NaBH4 / ethanol / 3 h / Heating 4: 84.4 percent / NaH / dimethylformamide; various solvent(s) / 0.5 h / 50 °C View Scheme
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
1: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) THF, -78 deg C -> RT 2: 5.9 percent / NaBH4 / ethanol / 3 h / Heating 3: 84.4 percent / NaH / dimethylformamide; various solvent(s) / 0.5 h / 50 °C View Scheme
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
1: 5.9 percent / NaBH4 / ethanol / 3 h / Heating 2: 84.4 percent / NaH / dimethylformamide; various solvent(s) / 0.5 h / 50 °C View Scheme
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
methyl 1-naphthyl ketone; lithium perchlorate; acetic acid 1) MeCN, 17 h, irradiation, 2) MeCN, anodic oxidation, 24-28 deg C; Yield given. Multistep reaction;
参考文献
Gates, Bradley D.; Swenton, John S.
Tetrahedron Letters, 1992 , vol. 33, # 16 p. 2127 - 2128
反应条件
potassium permanganate
参考文献
Naves; Ardizio
Bulletin de la Societe Chimique de France, 1957 , p. 1053,1056
反应条件
1: O2-O3; Zn; AcOH / methanol 2: 90 percent / I2; KOH View Scheme
参考文献
Gonzalez-Serratos, Hugo; Chang, Ruzhang; Pereira, Edna F. R.; Castro, Newton G.; Aracava, Yasco; Melo, Paulo A.; Lima, Patricia C.; Fraga, Carlos A. M.; Barreiro, Eliezer J.; Albuquerque, Edson X.
Journal of Pharmacology and Experimental Therapeutics, 2001 , vol. 299, # 2 p. 558 - 566
反应条件
sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride in tetrahydrofuran; water 0.025 h; microwave irradiation;
参考文献
Sinha, Arun K.; Joshi, Bhupendra P.; Acharya, Ruchi
Chemistry Letters, 2003 , vol. 32, # 8 p. 780 - 781
反应条件
1: O2-O3; Zn; AcOH / methanol 2: 90 percent / I2; KOH 3: 70 percent / N2H4*H2O / ethanol / 3.5 h / Heating View Scheme
参考文献
Gonzalez-Serratos, Hugo; Chang, Ruzhang; Pereira, Edna F. R.; Castro, Newton G.; Aracava, Yasco; Melo, Paulo A.; Lima, Patricia C.; Fraga, Carlos A. M.; Barreiro, Eliezer J.; Albuquerque, Edson X.
Journal of Pharmacology and Experimental Therapeutics, 2001 , vol. 299, # 2 p. 558 - 566
