(Z)-5-(丙烯-1-基)-1,3-苯并二氧戊环合成路线 （共 18 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=50°C; 1 h;
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Chemical Communications, 1981 , # 3 p. 100 - 101
反应条件
potassium hydroxide T=80°C; 0.0833333 h; other aryl-olefines; var. basic system, var. time and temp.;
参考文献
Luu, Thi Xuan Thi; Lam, Trinh To; Le, Thach Ngoc; Duus, Fritz
Molecules, 2009 , vol. 14, # 9 p. 3411 - 3424
反应条件
Isolierung durch fraktionierte Destillation;
参考文献
Gonzalez-Serratos, Hugo; Chang, Ruzhang; Pereira, Edna F. R.; Castro, Newton G.; Aracava, Yasco; Melo, Paulo A.; Lima, Patricia C.; Fraga, Carlos A. M.; Barreiro, Eliezer J.; Albuquerque, Edson X.
Journal of Pharmacology and Experimental Therapeutics, 2001 , vol. 299, # 2 p. 558 - 566
反应条件
sodium hydride in N,N-dimethyl-formamide T=50°C; 0.5 h;
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
1: ethyl-(2-methoxy-phenyl)-diphenyl-phosphonium; iodide With N,N,N',N',N'',N''-hexamethylphosphoric triamide; sec.-butyllithium in tetrahydrofuran; pentane T=-78°C; Wittig reaction; Inert atmosphere; 2: piperonal in tetrahydrofuran; pentane T=-78 - 20°C; Wittig reaction; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
Tetrahedron Letters, 2008 , vol. 49, # 49 p. 7054 - 7057
反应条件
1: C21H22OP(1+)*I(1-) With N,N,N',N',N'',N''-hexamethylphosphoric triamide; sec.-butyllithium in tetrahydrofuran; pentane T=-78°C; Wittig reaction; Inert atmosphere; 2: piperonal in tetrahydrofuran; pentane T=-78 - 20°C; Wittig reaction; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
Tetrahedron Letters, 2008 , vol. 49, # 49 p. 7054 - 7057
反应条件
1: C20H20OP(1+)*I(1-) With N,N,N',N',N'',N''-hexamethylphosphoric triamide; sec.-butyllithium in tetrahydrofuran; pentane T=-78°C; Wittig reaction; Inert atmosphere; 2: piperonal in tetrahydrofuran; pentane T=-78 - 20°C; Wittig reaction; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
Tetrahedron Letters, 2008 , vol. 49, # 49 p. 7054 - 7057
反应条件
1: (ethyl)-triphenylphosphonium iodide With N,N,N',N',N'',N''-hexamethylphosphoric triamide; sec.-butyllithium in tetrahydrofuran; pentane T=-78°C; Wittig reaction; Inert atmosphere; 2: piperonal in tetrahydrofuran; pentane T=-78 - 20°C; Wittig reaction; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
Tetrahedron Letters, 2008 , vol. 49, # 49 p. 7054 - 7057
反应条件
1: (ethyl)-triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran T=20°C; 1 h; 2: piperonal in tetrahydrofuran T=20°C; 6 h; Further stages. Title compound not separated from byproducts.;
参考文献
Schobert; Siegfried; Gordon
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 19 p. 2393 - 2397
反应条件
1: 1.) BuLi / 1.) THF/hexane, -78 deg C 2.) warming up to r.t. during 2 h 2: 84 percent / NaH / dimethylformamide / 1 h / 50 °C View Scheme
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Chemical Communications, 1981 , # 3 p. 100 - 101
