8-甲氧基-[1,2,4]噻唑并[1,5-a]吡啶-2-胺合成路线 （共 4 条）
反应条件
4-(N,N-dimethlyamino)pyridine; hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine in methanol; ethanol T=20 - 60°C; 5 h;
参考文献
Bleicher, Konrad H.; Nettekoven, Matthias; Peters, Jens-Uwe; Wyler, Rene
Chimia, 2004 , vol. 58, # 9 p. 588 - 600
反应条件
1: 97 percent / dioxane 2: 78 percent / NH2OH; DMAP / methanol; ethanol View Scheme
参考文献
Chimia, , vol. 58, # 9 p. 588 - 600
反应条件
sulfuric acid; sodium carbonate in water
参考文献
Hoffmann-La Roche Inc.
Patent: US6514989 B1, 2003 ;
反应条件
KIO3; sulfuric acid
T=120°C; 3 h;
参考文献
Bleicher, Konrad H.; Nettekoven, Matthias; Peters, Jens-Uwe; Wyler, Rene
Chimia, 2004 , vol. 58, # 9 p. 588 - 600
