2,2-二甲基环丙甲酰胺合成路线 （共 12 条）
反应条件
ammonia; sodium methylate in methanol; formamide T=80°C; P=1500.15 Torr; 5 h; Inert atmosphere; Concentration;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED; Tomokawa, Junichi; Kimura, Takahiro; Hirata, Norihiko
Patent: US2013/123505 A1, 2013 ;
Location in patent: Paragraph 0066 ;
反应条件
ammonia in diethyl ether 2 h;
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
phosphorus trichoride Behandlung des entstandenen Chlorids mit NH3;
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 145, p. 80
Bulletin de la Societe Chimique de France, , vol. <4>1, p. 1246
反应条件
1: 85 percent / NaOH / H2O / 48 h / Heating 2: 89 percent / Thionyl chloride 3: 98 percent / NH3 / diethyl ether / 2 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 12 p. 2489 - 2498
反应条件
1: 71 percent / ethane-1,2-diol / 2 h / Heating 2: 85 percent / NaOH / H2O / 48 h / Heating 3: 89 percent / Thionyl chloride 4: 98 percent / NH3 / diethyl ether / 2 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 12 p. 2489 - 2498
反应条件
1: 96 percent / pyridine 2: 71 percent / ethane-1,2-diol / 2 h / Heating 3: 85 percent / NaOH / H2O / 48 h / Heating 4: 89 percent / Thionyl chloride 5: 98 percent / NH3 / diethyl ether / 2 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 12 p. 2489 - 2498
参考文献
Bulletin de la Societe Chimique de France, , p. 1957 - 1963
反应条件
1: sodium compound of methylmalonic acid ester / Behandeln mit alkoh. Kalilauge 2: PCl3 / Behandlung des entstandenen Chlorids mit NH3 View Scheme
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 145, p. 80
Bulletin de la Societe Chimique de France, , vol. <4>1, p. 1246
反应条件
1: Br2 2: liq. NH3 View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 1957 - 1963
反应条件
1: (i) DMF, (ii) aq. NaOH 2: (i) SOCl2, (ii) liq. NH3 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 28, p. 1406 - 1409
