2-(二苯基甲氧基)-N-甲基乙胺合成路线 （共 6 条）
反应条件
tetrabutylammomium bromide; potassium carbonate in tetrahydrofuran T=20°C; 27.5 h;
参考文献
NEKTAR THERAPEUTICS AL, CORPORATION
Patent: WO2008/112257 A1, 2008 ;
Location in patent: Page/Page column 38 ;
参考文献
Falch; Krogsgaard-Larsen
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 1 p. 69 - 77
反应条件
1: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 10 min, 2) reflux, 2 h 2: 1) CH3OH, 2) NaOH / 1) r.t., 50 deg C, 2 h, 2) water View Scheme
参考文献
Wolf, Cornelia; Schunack, Walter
Archiv der Pharmazie, 1996 , vol. 329, # 2 p. 87 - 94
反应条件
potassium hydroxide T=100°C;
参考文献
Searle and Co.
Patent: US2577234 , 1947 ;
反应条件
1: Na2CO3 2: ethanol View Scheme
参考文献
Protiva et al.
Chemicke Listy, 1951 , vol. 45, p. 43
Chem.Abstr., 1951 , p. 9010
反应条件
in ethanol 336 h; Heating;
参考文献
Doege, Ulrica; Eger
Pharmazie, 2007 , vol. 62, # 3 p. 174 - 178
