2,3-二氢-2-甲基苯并呋喃合成路线 （共 55 条）
反应条件
1.1: DIBAL / toluene / 2 h / -78 °C 1.2: methanol; toluene / 1.5 h / -78 - 20 °C 2.1: 73 percent / tetrahydrofuran; diethyl ether / 1.5 h / -20 - 20 °C 3.1: 59 percent / (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; bis(dibenzylideneacetone) palladium(0); sodium tert-butoxide / toluene / 5 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 16 p. 5553 - 5566
反应条件
1: 73 percent / tetrahydrofuran; diethyl ether / 1.5 h / -20 - 20 °C 2: 59 percent / (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; bis(dibenzylideneacetone) palladium(0); sodium tert-butoxide / toluene / 5 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 16 p. 5553 - 5566
反应条件
1: hydrazine hydrate / ethanol / 0.25 h / 60 °C 2: 95 percent / n-Bu3SnH / toluene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 18 p. 4391 - 4397
反应条件
1: 42 percent / Na2SO4, acetaldehyde / 40 °C 2: 46 percent / Li, DTBB / tetrahydrofuran / 2 h / Ambient temperature 3: 57 percent / 85percent phosphoric acid / toluene / Heating View Scheme
参考文献
Tetrahedron, , vol. 53, # 51 p. 17373 - 17382
反应条件
1: 46 percent / Li, DTBB / tetrahydrofuran / 2 h / Ambient temperature 2: 57 percent / 85percent phosphoric acid / toluene / Heating View Scheme
参考文献
Tetrahedron, , vol. 53, # 51 p. 17373 - 17382
反应条件
in acetonitrile 1 h; Irradiation;
参考文献
Chemical Communications, , # 22 p. 2328 - 2329
反应条件
1.1: tert.-butyl lithium / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C / Inert atmosphere 2.1: [Ru(η4-COD)(η3-methylallyl)2]; potassium tert-butylate; hydrogen; ICy*HCl / hexane / 18 h / 60 °C / 48754.9 Torr / Autoclave View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 7 p. 1710 - 1713
反应条件
NMPTsO T=200°C; Claisen rearrangement; 4 h; Inert atmosphere;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 46, # 2 p. 158 - 169
反应条件
hydrogen bromide; hydroquinone erwaermen der in wss.Natronlauge unloeslichen Anteile des Reaktionsprodukts mit wss.-aethanol.Kalilauge;
参考文献
Journal of Organic Chemistry, , vol. 5, p. 212,218
反应条件
sodium hydroxide; sodium tetrahydroborate; mercury(II) diacetate 1) THF, H2O, RT, 1h, 2) THF, H2O, 25 deg C, 3h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 58, # 12 p. 3304 - 3307
