6,7-二甲氧基-1,2,3,4-四氢异喹啉合成路线 （共 60 条）
反应条件
N-Methylmaleinimide in water T=50°C; 4 h;
参考文献
Journal of the American Chemical Society, , vol. 109, # 19 p. 5859 - 5861
反应条件
butyl triphenylphosphonium tetraborate T=20°C; 0.1 h;
参考文献
Hajipour; Mohammadpoor-Baltork; Noroallhi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 2 p. 152 - 156
反应条件
formic acid Pictet-Spengler cyclization; 12 h; Heating;
参考文献
Louafi, Fadila; Hurvois, Jean-Pierre; Chibani, Aissa; Roisnel, Thierry
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5721 - 5724
反应条件
1: With iodine in methanol T=20°C; 7 h; 2: With zinc in methanol T=20°C; 0.5 h;
参考文献
Vatele, Jean-Michel
Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9127 - 9130
反应条件
naphthalene; tetraethylammonium bromide in N,N-dimethyl-formamide T=0°C; Inert atmosphereElectrolysis;
参考文献
Senboku, Hisanori; Nakahara, Kazuo; Fukuhara, Tsuyoshi; Hara, Shoji
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 435 - 438
反应条件
sodium hydroxide in ethanol 4 h; Ambient temperature;
参考文献
Shinohara, Tatsumi; Toda, Jun; Sano, Takehiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 813 - 819
反应条件
sodium hydrogencarbonate in water 0.5 h;
参考文献
WO2010/143803 A2, ;
Page/Page column 22 ;
WO 2010/143803 A2
反应条件
1: 73 percent / H2, HCl / 5percent Pd-C / ethanol / 24 h / 760 Torr / Ambient temperature 2: 80 percent / HCO2H View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 63, # 4 p. 1252 - 1254
反应条件
zinc dibromide in dichloromethane 4 h; Ambient temperature;
参考文献
Nigam, Satish C.; Mann, Andre; Taddei, Maurizio; Wermuth, Camille-Georges
Synthetic Communications, 1989 , vol. 19, # 18 p. 3139 - 3142
反应条件
sodium hydroxide in ethanol 18 h; Heating;
参考文献
Shinohara, Tatsumi; Toda, Jun; Sano, Takehiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 813 - 819
