(S)-(+)-α-甲基环己烷甲胺合成路线 (共 18 条)
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 264 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 9 p. 1759 - 1764
反应条件
1,3-dimethoxy-2-propanone; ωTA ATA-117 102907WW; Vibrio fluvialis Vf-ωTA 2100208MW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 10 p. 3286 - 3294
反应条件
lithium aluminium tetrahydride; 3-O-cyclohexylmethyl-1,2-O-cyclohexylidene-α-D-glucofuranose in diethyl ether 2.5 h; HeatingLiAlH4 concentration effect on enantiomeric excess; asymmetric reduction of ketones and isoelectronic ketone oximes with LiAlH4-3-O-cyclohexylmethyl-1,2-O-cyclohexylidene-α-D-glucofuranose complex; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 3 p. 493 - 496
反应条件
Raney Co; hydrogen in toluene T=70°C; P=150.015 Torr; 72 h; Autoclave;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 1 p. 113 - 121
反应条件
Ni T=110°C; 2 h; Inert atmosphere; Reagent/catalystTime;
参考文献
Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E.
European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628
反应条件
in ethanol
T=0 - 20°C; Yield given;
参考文献
Page, Philip C. Bulman; Rassias, Gerasimos A.; Bethell, Donald; Schilling, Mark B.
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2774 - 2777
反应条件
dicyclohexyl-carbodiimide in diethyl ether
T=-10 - 20°C; 15 h;
参考文献
Tsogoeva, Svetlana B.; Yalalov, Denis A.; Hateley, Martin J.; Weckbecker, Christoph; Huthmacher, Klaus
European Journal of Organic Chemistry, 2005 , # 23 p. 4995 - 5000