1-苯基-3-丁炔-1-醇合成路线 （共 77 条）
反应条件
1: With methyllithium in tetrahydrofuran; diethyl ether
T=0 - 20°C; Wittig rearrangement;
2: With ammonium chloride in tetrahydrofuran
Further stages.;
参考文献
Maleczka Jr., Robert E.; Geng, Feng
Organic Letters, 1999 , vol. 1, # 7 p. 1115 - 1118
反应条件
n-butyllithium in tetrahydrofuran
T=-78 - 0°C;
参考文献
Tomooka, Katsuhiko; Harada, Manabu; Hanji, Takayuki; Nakai, Takeshi
Chemistry Letters, 2000 , # 12 p. 1394 - 1395
反应条件
1: 1,1-Diisopropylbut-3-ynol With methyl-magnesium iodide in 1,4-dioxane
T=25°C; 1 h;
2: benzaldehyde With gallium(III) chloride in 1,4-dioxane; hexane
T=25°C; 1.5 h; Further stages.;
参考文献
Hayashi, Sayuri; Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro
Journal of Organometallic Chemistry, 2007 , vol. 692, # 1-3 p. 505 - 513
反应条件
in tetrahydrofuran
T=20°C;
参考文献
Wu, Chao; Huang, Wangyong; He, Weimin; Xiang, Jiannan
Chemistry Letters, 2013 , vol. 42, # 10 p. 1233 - 1234
反应条件
indium in methanol; water
12 h; Ambient temperatureother reagent; Product distribution;
参考文献
Yi, Xiang-Hui; Meng, Yue; Hua, Xiao-Gang; Li, Chao-Jun
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7472 - 7480
反应条件
in diethyl ether; N,N-dimethyl-formamide
T=0°C; 24 h;
参考文献
Schneider, Uwe; Sugiura, Masaharu; Kobayashi, Shu
Tetrahedron, 2006 , vol. 62, # 2-3 p. 496 - 502
反应条件
potassium iodide; tin(ll) chloride
T=35°C; 15 h;
参考文献
Houllemare, Didier; Outurquin, Francis; Paulmier, Claude
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 11 p. 1629 - 1632
反应条件
1: 3-isopropyl-2-methyl-hexa-4,5-dien-3-ol With methyl-magnesium iodide in 1,4-dioxane
T=25°C; 1 h;
2: benzaldehyde With gallium(III) chloride in 1,4-dioxane; hexane
T=25°C; 3 h; Further stages.;
参考文献
Hayashi, Sayuri; Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro
Journal of Organometallic Chemistry, 2007 , vol. 692, # 1-3 p. 505 - 513
反应条件
in dimethyl sulfoxide
T=0 - 20°C; Inert atmosphere;
参考文献
Liu, Fei Nian; Su, Fu Hai; Wen, Ting Bin; Sung, Herman H.-Y.; Williams, Ian D.; Jia, Guochen
Chemistry - A European Journal, 2010 , vol. 16, # 26 p. 7889 - 7897
反应条件
trichlorosilane; N-ethyl-N,N-diisopropylamine; copper(l) chloride
1.) Et2O, C2H5CN, 23 deg C, 12 h, 2.) Et2O, C2H5CN, DMF, 0 deg C, 12 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kobayashi, Shu; Nishio, Koichi
Journal of the American Chemical Society, 1995 , vol. 117, # 23 p. 6392 - 6393
