反应条件
1: (5R)-5-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolan-4-one With pyridinium chlorochromate in dichloromethane T=25°C; 4 h; 2: (S)-2-amino-4-methyl-pentanoic acid benzyl ester With acetic acid in methanol 0.5 h; 3: With sodium cyanoborohydride in methanol T=25°C; 3 h;
参考文献
Dutton, Fred E.; Lee, Byung H.; Johnson, Sandra S.; Coscarelli, Eileen M.; Lee, Pil H.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2057 - 2073
