3-氯-2,4,5,6-四氟吡啶合成路线 （共 40 条）
反应条件
ammonium formate; palladium on activated charcoal in octanol T=25°C; 6 h;
参考文献
Chemistry - A European Journal, , vol. 11, # 6 p. 1903 - 1910
反应条件
water; copper; zinc in N,N-dimethyl-formamide T=70°C; 8 h; Title compound not separated from byproducts;
参考文献
Russian Journal of Organic Chemistry, , vol. 29, # 5.2 p. 895 - 896
Zhurnal Organicheskoi Khimii, , vol. 29, # 5 p. 1078 - 1079
反应条件
catalyst: Pd on active carbon in not given Hydrogenation in presence of catalyst (10 percent Pd/90 percent active carbon) at 250 °C.;
参考文献
Journal of the Chemical Society, , p. 5045 - 5048
GB1134651 , ;
C.A., , vol. 70, p. 57661
反应条件
zinc in water; N,N-dimethyl-formamide 20 h; Heating;
参考文献
Russian Journal of Organic Chemistry, , vol. 36, # 10 p. 1488 - 1499
反应条件
in diethyl ether 122 h; Irradiation;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2520 - 2522
反应条件
sodium hydroxide in dichloromethane; chloroform; di-isopropyl ether
参考文献
Wakunaga Pharmaceuticals Co., Ltd.
Patent: US5998436 A1, 1999 ;
反应条件
in dichloromethane; N,N-dimethyl-formamide T=40°C; 24 h;
参考文献
Sakthivel, Kandasamy; Cook, P. Dan
Tetrahedron Letters, 2005 , vol. 46, # 22 p. 3883 - 3887
反应条件
potassium hydroxide in water 85 °C, 3 h;;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4.1.1.3, page 180 - 219
反应条件
potassium hydroxide in tert-butyl alcohol (19)F-NMR spectroscopy;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4.1.1.3, page 180 - 219
反应条件
zinc in water; N,N-dimethyl-formamide 20 h; Heating;
参考文献
Krasnov; Platonov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 10 p. 1488 - 1499
