1: methyl(diphenyl)phosphine oxide With n-butyllithium in tetrahydrofuran
T=0°C; 0.25 h;
2: ethyl acetate in tetrahydrofuran
T=-78°C; 3.5 h; Further stages.;
参考文献
Fox, David J.; Pedersen, Daniel Sejer; Warren, Stuart
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 16 p. 3102 - 3107
Angelova, Olyana; Kirilov, Emil M. G.; Kirilov, Marko; Petrov, Galin; Kaneti, Jose; Macicek, Josef
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1405 - 1408
1: triethylamine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
2: water; silica gel / Inert atmosphere
View Scheme
参考文献
De Los Santos, Jesus M.; Ignacio, Roberto; Rubiales, Gloria; Aparicio, Domitila; Palacios, Francisco
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6715 - 6725