potassium hydroxide; hydrazine hydrate in methanol; diethylene glycol 125 deg C, 6 h; 195 deg C, 3 h;

1: pyridine / 1 h / 0 °C 2: LiBr / acetone / 5 h / Heating 4: KOH / ethanol; H2O / 5 h / Heating 5: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: 1.) Ba(OH)2*8H2O; 2.) HCl / methanol 2: SOCl2 / 1 h / Ambient temperature 4: KOH / ethanol; H2O / 5 h / Heating 5: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

2: KOH / ethanol; H2O / 5 h / Heating 3: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: H2SO4 / 1 h / Heating 2: 1.) LiAlH4; 2.) HCl / 1.) diethyl ether, 8 h, reflux; 2.) 0 deg C, water 3: pyridine / 1 h / 0 °C 4: LiBr / acetone / 5 h / Heating 6: KOH / ethanol; H2O / 5 h / Heating 7: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: 1.) LiAlH4; 2.) HCl / 1.) diethyl ether, 8 h, reflux; 2.) 0 deg C, water 2: pyridine / 1 h / 0 °C 3: LiBr / acetone / 5 h / Heating 5: KOH / ethanol; H2O / 5 h / Heating 6: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

2: KOH / ethanol; H2O / 5 h / Heating 3: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: SOCl2 / 1 h / Ambient temperature 3: KOH / ethanol; H2O / 5 h / Heating 4: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: 1.) 30 min, 150 deg; 2.) in 15 min to 180 deg C 2: H2SO4 / 1 h / Heating 3: 1.) LiAlH4; 2.) HCl / 1.) diethyl ether, 8 h, reflux; 2.) 0 deg C, water 4: pyridine / 1 h / 0 °C 5: LiBr / acetone / 5 h / Heating 7: KOH / ethanol; H2O / 5 h / Heating 8: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme

1: aqu. KOH / ethanol / 5 h / Heating 2: 1.) 30 min, 150 deg; 2.) in 15 min to 180 deg C 3: H2SO4 / 1 h / Heating 4: 1.) LiAlH4; 2.) HCl / 1.) diethyl ether, 8 h, reflux; 2.) 0 deg C, water 5: pyridine / 1 h / 0 °C 6: LiBr / acetone / 5 h / Heating 8: KOH / ethanol; H2O / 5 h / Heating 9: 83 percent / N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 125 deg C, 6 h; 195 deg C, 3 h View Scheme