(S)-(+)-2-甲基丁酸合成路线 （共 111 条）
反应条件
lt;RuCl2(S)Biphempgt;2; hydrogen; triethylamine in methanol T=20°C; P=3040 Torr; 24 h;
参考文献
Genet, J. P.; Pinel, C.; Ratovelomanana-Vidal, V.; Mallart, S.; Pfister, X.; et al.
Tetrahedron: Asymmetry, 1994 , vol. 5, # 4 p. 675 - 690
反应条件
chromium(VI) oxide in acetone T=20°C; Oxidation; 2 h;
参考文献
Tashiro, Takuya; Mori, Kenji
European Journal of Organic Chemistry, 1999 , # 9 p. 2167 - 2173
反应条件
hydrogen; triethylamine; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in ethanol; benzene 24 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Yamashita, Mitsuji; Kobayashi, Mineaki; Sugiura, Motoyuki; Tsunekawa, Kenji; Oshikawa, Tatsuo; et al.
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 1 p. 175 - 178
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran 0.333333 h; Yield given;
参考文献
Chu, Kent S.; Negrete, George R.; Konopebki, Joseph P.; Lakner, Frederick J.; Woo, Nam-Tae; Olmstead, Marilyn M.
Journal of the American Chemical Society, 1992 , vol. 114, # 5 p. 1800 - 1812
反应条件
sodium azide; tris-hydrochloride buffer; oxygen; Crotalus adamanteus venom L-amino acid oxidase T=30°C; Oxidation; pH=7.2; 48 h;
参考文献
Bakke, Mikio; Ohta, Hiromichi; Kazmaier, Uli; Sugai, Takeshi
Synthesis, 1999 , # 9 p. 1671 - 1677
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran T=0°C; Ring cleavage; Hydrolysis; 2 h;
参考文献
Harding, John R.; Hughes, Rachael A.; Kelly, Nicholas M.; Sutherland, Andrew; Willis, Christine L.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3406 - 3416
反应条件
hydrogenchloride T=100°C; 2 h;
参考文献
Evans, D. A.; Takacs, J. M.
Tetrahedron Letters, 1980 , vol. 21, p. 4233 - 4236
反应条件
hydrogen; triethylamine; (R)-lt;RuI(p-cymene)(2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl)gt;I in methanol T=25°C; 2 h; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 34, # 14 p. 2351 - 2354
反应条件
kieselgel; ozone T=-78°C;
参考文献
Schoenfelder, Wolfgang; Snatzke, Guenther
Chemische Berichte, 1980 , vol. 113, # 5 p. 1855 - 1866
反应条件
sulfuric acid in 1,4-dioxane 4 h; Heating;
参考文献
Bestmann, Hans Juergen; Frighetto, Rosa T. S.; Frighetto, Nelson; Vostrowsky, Otto
Liebigs Annalen der Chemie, 1988 , p. 877 - 880
