4,6-二氯吡嗪-3(2H)-酮合成路线 （共 5 条）
参考文献
Schoenbeck,R.; Kloimstein,E.
Monatshefte fuer Chemie, 1968 , vol. 99, p. 15 - 81
Full Text View citing articles Show Details
Eichenberger et al.
Helvetica Chimica Acta, 1956 , vol. 39, p. 1755,1762
参考文献
Schoenbeck,R.; Kloimstein,E.
Monatshefte fuer Chemie, 1968 , vol. 99, p. 15 - 81
参考文献
Schoenbeck,R.; Kloimstein,E.
Monatshefte fuer Chemie, 1968 , vol. 99, p. 15 - 81
Full Text View citing articles Show Details
Eichenberger et al.
Helvetica Chimica Acta, 1956 , vol. 39, p. 1755,1762
参考文献
Schoenbeck,R.; Kloimstein,E.
Monatshefte fuer Chemie, 1968 , vol. 99, p. 15 - 81
Full Text View citing articles Show Details
Kuraishi
Pharmaceutical Bulletin, 1957 , vol. 5, p. 376,377
Pharmaceutical Bulletin, 1958 , vol. 6, p. 641
反应条件
1: 4,6-dichloro-2H-pyridazin-3-one With sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C; 0.5 h;
2: methyl iodide in N,N-dimethyl-formamide
T=10 - 20°C; 4.0833 h;
参考文献
Roche Palo Alto LLC
Patent: US2009/105209 A1, 2009 ;
Location in patent: Page/Page column 47 ;
US 20090105209 A1
