(R)-(-)-2-甲基哌啶合成路线 （共 18 条）
反应条件
hydrogen; acetic acid; palladium dihydroxide T=50°C; P=75006 Torr; 22 h; Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 21 p. 2850 - 2852
反应条件
hydrogen; palladium on activated charcoal
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 359 - 363
反应条件
in dichloromethane T=5°C; Acylation; Kinetic resolution; 24 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 1 p. 43 - 44
参考文献
Synlett, , # 1 p. 122 - 124
反应条件
1: 62 percent / Grubb's ruthenium catalyst / CH2Cl2 / 24 h / 20 °C 2: 90 percent / H2 / Pd/C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 359 - 363
反应条件
1: 81 percent / sodium cyanoborohydride / pH = 3 2: H2 / Pd-C / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 39 p. 6329 - 6332
反应条件
sodium hydroxide in water
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7560 - 7570,11
Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7560 - 7570
反应条件
1: 85 percent / diethyl ether / 0.5 h / 20 °C 2: 93 percent / H2 View Scheme
参考文献
Synlett, , # 1 p. 122 - 124
反应条件
1: NaBH3CN / CH2Cl2; methanol / 20 °C 2: 85 percent / diethyl ether / 0.5 h / 20 °C 3: 93 percent / H2 View Scheme
参考文献
Synlett, , # 1 p. 122 - 124
反应条件
in dichloromethane T=5°C; Acylation; 72 h;
参考文献
Tetrahedron Letters, , vol. 41, # 13 p. 2239 - 2242
