3-乙酰基-2-甲基吡啶合成路线 （共 13 条）
反应条件
1: sulfur; dioxane; aqueous <NH4>2S / 175 - 180 °C
2: P2O5
3: platinum; H2O / Hydrogenation
4: aqueous sulfuric acid; aqueous sodium nitrite
View Scheme
参考文献
TEMPERO PHARMACEUTICALS, INC.; BALOGLU, Erkan; GHOSH, Shomir; LOBERA, Mercedes; SCHMIDT, Darby, R.
Patent: WO2013/19621 A1, 2013 ;
WO 2013/019621 A1
反应条件
1: sulfur; dioxane; aqueous <NH4>2S / 175 - 180 °C
2: P2O5
3: platinum; H2O / Hydrogenation
View Scheme
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
反应条件
1: hydrazine hydrate / 125 °C / Erhitzen des Reaktionsprodukts mit Kaliumhydroxid auf 150grad
2: water; hydrogen peroxide / anschliessenden Erwaermen mit Acetanhydrid
3: aqueous hydrochloric acid
4: diethyl ether; manganese (IV)-oxide
5: Ag2O; H2O
View Scheme
参考文献
Nakashima
Yakugaku Zasshi, 1958 , vol. 78, p. 661,665
Chem.Abstr., 1958 , p. 18399
