(S)-(+)-扁桃酸合成路线 （共 229 条）
反应条件
1: 66 percent / DIPEA / CH2Cl2 2: 98 percent / TBAF / tetrahydrofuran 3: 92 percent / TEMPO; NAOCl; NaOCl2 / aq. phosphate buffer; acetonitrile / 55 °C / pH 6.5 4: 92 percent / ZnBr2 / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 17 p. 3209 - 3213
反应条件
1: 92 percent / TEMPO; NAOCl; NaOCl2 / aq. phosphate buffer; acetonitrile / 55 °C / pH 6.5 2: 92 percent / ZnBr2 / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 17 p. 3209 - 3213
反应条件
1: 98 percent / TBAF / tetrahydrofuran 2: 92 percent / TEMPO; NAOCl; NaOCl2 / aq. phosphate buffer; acetonitrile / 55 °C / pH 6.5 3: 92 percent / ZnBr2 / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 17 p. 3209 - 3213
反应条件
1: LDA 2: 50 percent / F2 / acetonitrile; H2O; CHCl3 / 0 - 20 °C View Scheme
参考文献
Tetrahedron, , vol. 55, # 12 p. 3657 - 3664
反应条件
1: 70 percent / triethylamine / tetrahydrofuran / 3 h / -20 °C 2: 63 percent / cc. aq. HCl / 12 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 50 p. 9209 - 9210
反应条件
T=160°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 16, p. 2720
反应条件
sulfuric acid; sodium nitrite T=0°C; racemic mandelic acid;
参考文献
Chemische Berichte, , vol. 41, p. 1288
反应条件
water T=180°C; im geschlossenen Rohr; racemic mandelic acid;
参考文献
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 29, p. 111
Chem. Zentralbl., , vol. 68, # I p. 1015
反应条件
calcium hydroxide powder; dicobalt octacarbonyl; methyl iodide in 1,4-dioxane; water 20 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 12 p. 2623 - 2625
反应条件
sodium hydroxide; sodium hypochlorite in methanol T=28°C; 8 h;
参考文献
Canadian Journal of Chemistry, , vol. 69, # 12 p. 1904 - 1908
