1-氨基-1-环戊烷羧酰胺合成路线 （共 9 条）
反应条件
1: With sulfuric acid in dichloromethane T=15 - 40°C; 1 h; 2: With ammonia in dichloromethane; water T=0°C; pH=7 - 8;
参考文献
Neurochem (International) Limited
Patent: US2006/223855 A1, 2006 ;
Location in patent: Page/Page column 157 ;
反应条件
sulfuric acid T=20°C; 0.75 h;
参考文献
Cousaert, Nicolas; Willand, Nicolas; Gesquiere, Jean-Claude; Tartar, Andre; Deprez, Benoit; Deprez-Poulain, Rebecca
Tetrahedron Letters, 2008 , vol. 49, # 17 p. 2743 - 2747
反应条件
hydrogen; palladium on activated charcoal in methanol; water
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 5, p. 531 - 540
反应条件
1: (i) Et3N, ClCO2Et, THF, (ii) NH3 2: H2 / Pd-C / methanol; H2O View Scheme
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 5, p. 531 - 540
反应条件
1: NaOH 2: (i) Et3N, ClCO2Et, THF, (ii) NH3 3: H2 / Pd-C / methanol; H2O View Scheme
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 5, p. 531 - 540
反应条件
water in diethyl ether
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 37, p. 856 - 859,805 - 808
反应条件
(i) Et3N, Et2O, (ii) aq. NH3; Multistep reaction;
参考文献
Journal of the Chemical Society, , p. 2119 - 2132
反应条件
potassium carbonate in dichloromethane; water T=0 - 20°C;
参考文献
KRKA, tovarna zdravil, d.d., Novo mesto
Patent: EP2194050 A1, 2010 ;
Location in patent: Page/Page column 10; 11 ;
反应条件
potassium hydroxide in tetrahydrofuran; methanol 2.5 h; Heating;
参考文献
Cousaert, Nicolas; Willand, Nicolas; Gesquiere, Jean-Claude; Tartar, Andre; Deprez, Benoit; Deprez-Poulain, Rebecca
Tetrahedron Letters, 2008 , vol. 49, # 17 p. 2743 - 2747
