2,4,6-三甲基-3-硝基苯酚合成路线 （共 7 条）
反应条件
sodium hydroxide in tetrahydrofuran; methanol Hydrolysis; 0.25 h;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
1: Et3N 2: 70 percent HNO3; conc. H2SO4; AcOH / 1 h 3: 2 N NaOH / tetrahydrofuran; methanol / 0.25 h View Scheme
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
1: 70 percent HNO3; conc. H2SO4; AcOH / 1 h 2: 2 N NaOH / tetrahydrofuran; methanol / 0.25 h View Scheme
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
1: aq. NH3, H2S / ethanol / Heating 2: (i) aq. H2SO4, NaNO2, (ii) (heating) View Scheme
参考文献
Stein,A.R.
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1493 - 1507
反应条件
1: HNO3 2: aq. NH3, H2S / ethanol / Heating 3: (i) aq. H2SO4, NaNO2, (ii) (heating) View Scheme
参考文献
Stein,A.R.
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1493 - 1507
反应条件
(i) aq. H2SO4, NaNO2, (ii) (heating); Multistep reaction;
参考文献
Stein,A.R.
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1493 - 1507
反应条件
(i) Sn, aq. HCl, (ii) NaNO2, aq. H2SO4, (iii) (heating); Multistep reaction;
参考文献
Stein,A.R.
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1493 - 1507
