2-甲基-4-苯基-3-丁炔-2-醇合成路线 （共 97 条）
反应条件
copper(l) iodide; lithium carbonate in dichloromethane
T=70°C; Inert atmosphere; regioselective reaction;
参考文献
Xu, Ze-Feng; Cai, Chen-Xin; Liu, Jin-Tao
Organic Letters, 2013 , vol. 15, # 9 p. 2096 - 2099
反应条件
triethylsilane; calcium triflimide; nBu4NPF6 in dichloromethane
T=20°C; 1 h; chemoselective reaction;
参考文献
Meyer, Vera J.; Niggemann, Meike
Chemistry - A European Journal, 2012 , vol. 18, # 15 p. 4687 - 4691
反应条件
AlCl3, aluminium chloride; lithium aluminium tetrahydride in tetrahydrofuran
T=70°C; 5 h; ConcentrationSolvent; Overall yield = 82 percent;
参考文献
Cui, Dong-Mei; Zhu, Kai; Chen, Li; Qi, Lang-Jun; Zhang, Cheng-Zhu; Zheng, Chen
Synthetic Communications, 2013 , vol. 43, # 17 p. 2380 - 2384
参考文献
Skossarewski
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1905 , vol. 37, p. 646
Chem. Zentralbl., 1905 , vol. 76, # II p. 1018
反应条件
sodium hydroxide; copper(l) iodide; tetra-(n-butyl)ammonium iodide; bis-triphenylphosphine-palladium(II) chloride in toluene
T=80°C; Sonogashira coupling; 24 h;
参考文献
Chow; Wan; Low; Yeung
Journal of Organic Chemistry, 2001 , vol. 66, # 5 p. 1910 - 1913
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
succinic acid; polyvanadioorganosiloxane (4percent V); Ph2Si(OH)2 in various solvent(s)
T=146 - 150°C;
参考文献
Erman, M. B.; Pribytkova, I. M.; Gulyi, S. E.; Bogomolova, O. A.; Cherkaev, G. V.; et al.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 12.2 p. 2294 - 2301
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 12 p. 2557 - 2565
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
sodium hydroxide; copper(l) iodide in butan-1-ol
24 h; Heating;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
